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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0658b081866dbb0a859f9df0f8c4586d5368da77809aea3a361f28c85b1db2e' 
  AND token = 'diOFVSVo1BSQc59ZW+3O1aHM80ETh0Jd6NKDwFjhphc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}