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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f12f7cd3ffc9c053256e74d99d009e0fcd50eae0dae5b14185f30477ea0a0155' 
  AND token = 'VlAn+oOqyjFiNn2axhkdrMyJgQTTcPAyCZlBYfsMtu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}