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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7274409603ebe0498d0c3be624b32c3762824d085c552168982c8851ac8c4ac2' 
  AND token = 'pujuu3eVPXHKmTQ9zb7pZQWN/BGXUzZPrb+tmKs4ch4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}