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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4345d7c4224c8f2001918b4fb1ea9550e898a0d89163db986ca6874c2adb3d4c' 
  AND token = 'T/P4IdpH3vjyFH2gr842SPjD3qQBziZX49Uq3ezoR1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}