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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5225aec0493ff4ff22c6626b9ac30d5fe5b8884c82249aede76ba0018f9516bb' 
  AND token = 'dLc1UyYeQc5FeyzSlZ4XxGGHaIGeri9C9LueTEdiXm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}