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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2e52a24675188daf926c2f40ad5f6137631a6c2aee08437e8a7e6dbc86820b' 
  AND token = 'u6UAhw/GobAoia5Rndc872SIXegAhhGzJP4p5OS9ZQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}