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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20935184c1a628b9b75779c7602c9f2cfa4ff3cf7f41427fdb45e10bb8b0ec27' 
  AND token = '4rHtQvJQ/xLLwDwE4NdKvmXAJNAIUWvUARAEUNoKwAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}