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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181fa4b481c23e28b43853a65142e70eaa7ace54f1794a00874fcfd8137a82a8' 
  AND token = '22SSh3UIo08KF2pz9kPIPUoKCkLRQ+1iuOL39VI9Z5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}