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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b66f42b377db3b89f54caf32b96fcb38af80f30774fbb293b8119f1c08b1b4b' 
  AND token = '1CE5R4Qg4AQVWcFRN57R0dM4QNC74kMlVcuMKP6RDh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}