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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390dfe56ea0055f1483ac9f2b0278b2fc18dbf79869fb1ec91bc3afd01822390' 
  AND token = 'ZE5WpNF6cHMYNtQcSxF+eK3sFnQmJrY13Gxoq+SATRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}