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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2ec6e033eee4ce890373120543c7326171d771cd86b7bc8e649c21807efaf06' 
  AND token = 'Y5r3Q8WZ+zkxRqHiaIdBQdnNtaLOCHryj++DKNTbMe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}