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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad6f35131773f9b31c600a3d33e6e74a449c41c8ec5e4fc6e1db37ba96f4587' 
  AND token = 'ymrPxrF8wx80O+3J6lCkwr9lCb5KcYUQCUXYpn1a8Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}