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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c5cec590dc33f5387c495d9b8d4f44d943b99f34af2300d980a549a8c8ea3ae' 
  AND token = 'ldBO2GpuqCByBiidE7AOi/d8miFCL31hi/vhpKUpJYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}