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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4446db1a3c5112a81fa336a57df66fb506bb45621d1b74a9a34d19f0a9a3d277' 
  AND token = 'kG0ziy0VyRQuLFFAisWLE3wRbSPKyzFP0CyPm44NkfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}