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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef9d12593d8056429db0bcfe0d8903218ff0d8bc6944d44bfea9c7a35fcc5bce' 
  AND token = 'uPCx2noPv0PKXLQiaNvGs8GuVQ3U8vzhiZHF+4n3wm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}