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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e307f00e226bfae5530d2c36225f5665ce08a64be575976a92afdc33f46d63c' 
  AND token = 'uBqL6Q4tGCD+QuWOZOncfVhFsK6B9gy+W0LV7mpr6Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}