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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a01ad1f86343abd97ecbd684c37d8f39e8b9675b672f172a3ca8c1b2c52819d8' 
  AND token = 'RcOE1G529xX6EzwsSPnCMjBZN+Qh+ZqpEi8tTsnxGy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}