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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a8002ba733edf9c249c9ade727aa9b742802bbd6e736fd00af8fd382876d95' 
  AND token = 'PWsBTl5g+T2HhJJAE7V3qWOl+5PHLVpkgGf3KAQWg5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}