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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4745b20221834fef181f8bdadf44ff72b149d44f6fc428337e6eb9a82a4f401' 
  AND token = 'oOcm9doMG5c8SjGAG7boru+EoCxGlfniah9E7D3B7O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}