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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18c2cc3f587207a767c9c0f771070f99b86049b4963de5390155702d25b7a80d' 
  AND token = 'NDYJPpKJxd7v6dC73NdjY2372MgSB+wkfgIxiojPcgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}