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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c1c2b84e619489d83deb8780efad1ce024e98fa81b936b2228e6205fd6fdac' 
  AND token = 'yHxwmk1/kv41lpG/VtyJTHR8Qt8regfw3Nw1LpOWN8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}