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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea23d8ac6d65d6af9cacde173e8422c20df8e5af1c7df337504903f4d7a48a5c' 
  AND token = 'B5MgaCXr07Msj3o4GT3xz5hrKWFxb5JHhwE6PUqM3kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}