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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '945d9aa298291a55208d4f087014f01f3d3063aa3d3b867e9777d5ee311ae52f' 
  AND token = 'DxEVNZaO5AKXrUbPL8Cq4/8uIBVyo5veF06jEIz9eUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}