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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225a8b8615f97952163b192dc9492caeca07a6b3094bb5eb8e08a431c0b76e4e' 
  AND token = 'gYPR18l4rjOFcJyGanXSZTTtwgRVj7RPEET8Q39/WgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}