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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14d40c9c1e92e79e7783acaf7ddf8b9617258bc207265b1bfdd378bcf7d21a54' 
  AND token = 'EDxCC499t/HROS7yJMtzLJpzMBSPmfrtIe3MZYVtFVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}