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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e037a7169c57ab07df1495d51bf8c4ae36200cd8c704ad44039bd8a7d4cdce48' 
  AND token = 'DpHCLl8L/FT5qxiYjJVDHpZAqBVsD5kCnJbN3XpcBfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}