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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3258cbc83358e8ccaed9f62ff05667f63103fdf5fc6d54aaee914a46e56593' 
  AND token = 'Tmpjm4aYgj4ouTG8XPSsV9nsIx7F+1aiQ4pFsrwxSL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}