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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb8bc0ff77ab2cc28b424d6c638add9b84d0c33e9632325db4aa39e3645a4a61' 
  AND token = 'QdCCc2NO6J7qBfLletNvKsV6XuGmtA1ehMSATKHgGKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}