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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd5078c3d797467b4214111a18a4a93b9c8d1401778bb3f50a16e08d91e7f3ef' 
  AND token = 'P9zjUMCCeK0W2lkBnv0aLM8Q5mnWu8oOsdkc3wFeoV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}