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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5242617baf99d7fd0043abb05e0e6d1f122a28134189481bcc12cb659c21394' 
  AND token = 'y+sZmxUwkC6RNDbyc1iuA0JRfOtfQb3jEOjTRVoa/C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}