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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72af48530792c3ee185db9f060dea37f8b7163cc6c034ac9da06ecb820f599b' 
  AND token = 'vZ9rpMrPOiM3yU3Dk5AVxiH1dHkn8rhLUZ20nMQ4Rts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}