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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd07a8c400852b5912728a2fa9af235ca2a9e1cb1b4e4b739747d4342a5832317' 
  AND token = 'qnGpJ3w+TXFZGG7AYU1+F51G5iTiPKHtLhdoaIbb4m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}