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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a51483436675f341877ec39b0616f02963cd31561778b7af7526efddf2e7dbe0' 
  AND token = 'zpyf8kh1PoVL7hMSTVxsjVMCguyQQTZ+Rxi+Nks47cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}