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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ddff1f66d1b4ebb27a30ed92f72cb28f55455bdaac697831dafc617a6ff1ba4' 
  AND token = 'kpjeY9dVd9t/kZPHL9n58d1Nl8JaXXA3l5oKAkOnliM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}