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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0763016ed7ae1f00b9f876e9a219e0a349be45d3f04adb73eab19ee884ca04a2' 
  AND token = 'w0J6oWNX7OLu1DcjOoEeWVLinHrt7bEvyT9Oq4lxPG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}