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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42acdf0688191ce6f5905e71e08ad673aabe00a7dbc0a97c848ec81c3c8bdbea' 
  AND token = 'GleVEBotsKhey8YeLewQd10tu9kj75QBvrI5acGcSvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}