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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc904cfb23692c1dd73ff0e370c87e269d22b958e949bff426764450736e0e90' 
  AND token = 'kFeAaHdEX4ASYo6+ga/a87leRUUyW4CcZRdFSD232ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}