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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8c2ef802f3917b9234df6b4b343f3d1d16375239668679f680a4a088e1685d1' 
  AND token = 'gJo+V3JLoSkRNZoI+rydlF6h63IdkNHB2DJqBQ15r9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}