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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59706cf47917623af84bcd79dd5edf4641d6fef697e890e6dbba1715e3d6c878' 
  AND token = 'Bob+VO3yA18hdYlpiO/LiWX2QYSwk7eeX2oCVpfmdOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}