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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec48508dc1f13f0c3b2d4dfe5df989288d520def16f9e371dc9c1d02944ce057' 
  AND token = 'rxNWsQnKAPDpp/cuiX2dm9DoHXnUsA7K6Ou9ysK/vuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}