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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6841d2e282da3f2af184058e6dbb78a252a74ca9a4489004074c58526a5265a' 
  AND token = 'VB1E2bk4kkm5RjNLg+6kE5rnDh1GZfo9CWvsKqG0seM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}