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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38da5a7f3707d2d44d52a01b7187d508b9a50efc36ff3181ab9b7740402b486f' 
  AND token = 'L0c8UZmGoFUfouCvFvypMDs8C32H0VCuH9Q7p5Gbr7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}