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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cd91fd3279f0121a91f63849e18d43b67ecfbcad71390e4d1f3b22b83f13181' 
  AND token = '46XRgGBNuvDgU+bcDN2UoHjg6+80lY8SezvBiE1+W9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}