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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0cf5a79b1efb832782b9226dbe2a49f8352eb59af436370d06c64fd5dff4d6' 
  AND token = '1+1TxmVWFUODUjM0YG3qLUR9EUvQFizerCtn0c6yrss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}