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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e589a692f84bc135a46c03cda0a384126bc52b176940a9c30e580a2a5ffceabb' 
  AND token = 'mdwFtza4DXoxSebVjl786t6wXtqi4fR5ESjhpTp0tfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}