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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba648e5445c7772d3af071946266060014c040d5dcc6deb0781d3b27c0c45099' 
  AND token = 'bfMtCMX4hq07Bcva0Lxv+h5uAWq3XQzzNOn0j3m6uGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}