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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '707b3aaa5a4f3cb4ae0e190cd7afb832d42c91cc7bfc004a82900f81761e1e76' 
  AND token = 'zuWfaj84u3Xw+dmyx3Ov8tFWxKIj39OZUt2bSCOxp6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}