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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5606c46a4ab9bb6e5fba57b196da22c449eb8049bd68ed41c27cb8934deee15d' 
  AND token = 'QtBrWlQpH+t5gxun9cNtpvLPdJ0ZHF/x1A68UxJMVyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}