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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4881b0f729019b0d6a36dca78ce25f5ab4b7309cab8c2fd63ca3e61188c0fee' 
  AND token = '9Kh+0JlSuUbbS03ArfeU0vQw9NQLZlslRZTWRGF6zhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}