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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '115c43e3dde366186bacb05edb0d8f084bca029aef350c892a0562868e3b7353' 
  AND token = '9Qj2DNI2+2mtA0FX2RE/RxFPDxcNNLhH0WE2EKW9SJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}